My doctor is thinking about adding an angiogenesis inhibitor to my treatment. What does that drug do and why do I need it?

Expert Opinion published on June 28, 2013 in Treatment
Download Transcript Download Audio
A. Oliver Sartor, MD
C.E. and Bernadine Laborde Professor of Cancer Research
Medical Director
Tulane Cancer Center
New Orleans, Louisiana
My doctor is thinking about adding an angiogenesis inhibitor to my treatment. What does that drug do and why do I need it?

Hello, my name is Dr. Oliver Sartor. I am the Laborde professor for cancer research at the Tulane Cancer Center and also the medical director there. I am often asked a variety of questions, and one question is that my doctor is thinking about adding an angiogenesis inhibitor to my treatment. What does that drug do and why do I need it? Well, the truth is we now have a fair amount of data about angiogenesis inhibitors in prostate cancer, and the answer is, do not do it, they do not work. We have looked at a number of them, and the most recent one is with aflibercept, which is a drug that is FDA-approved in the context of the metastatic colon cancer. We have looked at it in the context of bevacizumab, which has been approved in the variety of cancers, but it turns out in prostate cancer that angiogenesis inhibitors do not add to what we do ordinarily, and the bottom line is you do not need it.

Last modified: June 28, 2013
Related Items by Category
What are the new treatments that are now available for prostate cancer?
A. Oliver Sartor, MD
Expert Opinion published on June 28, 2013 in Treatment
My doctor told me prostate cancer spread to my bones. Is there any way for me to stop that from happening?
Daniel Petrylak, MD
Expert Opinion published on June 28, 2013 in Treatment
Should I be switching from my current therapy? When do you switch to something new?
A. Oliver Sartor, MD
Expert Opinion published on June 28, 2013 in Treatment
If I am diagnosed with prostate cancer, what do I do?
Dan Zenka, APR
Expert Opinion published on January 13, 2012 in Treatment
What is the best way to treat cancer of the prostate?
Donald L. Trump, MD, FACP
Expert Opinion published on January 13, 2012 in Treatment
How can I be told I have cancer of the prostate, yet also be told it does not need to be treated?
Donald L. Trump, MD, FACP
Expert Opinion published on January 13, 2012 in Treatment
How does hormone therapy work in prostate cancer?
Donald L. Trump, MD, FACP
Expert Opinion published on January 13, 2012 in Treatment
Is hormone therapy useful with surgery or radiation treatment?
Donald L. Trump, MD, FACP
Expert Opinion published on January 13, 2012 in Treatment
Is there any other treatment for prostate cancer once hormone therapy has stopped working?
Donald L. Trump, MD, FACP
Expert Opinion published on January 13, 2012 in Treatment
Does chemotherapy work in prostate cancer?
Donald L. Trump, MD, FACP
Expert Opinion published on January 13, 2012 in Treatment
Are there any new treatments for prostate cancer?
Donald L. Trump, MD, FACP
Expert Opinion published on January 13, 2012 in Treatment
Is there a new prostate cancer vaccine?
Donald L. Trump, MD, FACP
Expert Opinion published on January 13, 2012 in Treatment
Related Items by Author
Outcomes from ALSYMPCA and analysis of dtx on sipuleucel-T in PROCEED patients
A. Oliver Sartor, MD
Expert Opinion published on August 5, 2013 in ASCO 2013 Highlights
What are the new treatments that are now available for prostate cancer?
A. Oliver Sartor, MD
Expert Opinion published on June 28, 2013 in Treatment
Should I be switching from my current therapy? When do you switch to something new?
A. Oliver Sartor, MD
Expert Opinion published on June 28, 2013 in Treatment